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5.2 Assessing quality

Assessment of overall quality of scientific evidence
The quality of evidence reflects the extent to which confidence in an estimate of the effect is adequate to support recommendations.

  • The higher the quality of evidence the more likely the recommendation will be a strong one

  • The lower the quality of evidence the more likely the recommendation will be a conditional one

GRADE rates the quality of evidence for each outcome separately:

  • The source of evidence may be different for different outcomes;
  • The same source of evidence can provide varying quality of evidence for the different outcomes.