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HIV drug resistance
Learning objectives
Content and author
1. HIV resistance
2. Quasispecies
3. Resistance to ARVs
4. Adherence and resistance
5. Why is it important to take the right dose of medications?
6. Where does drug-resistant HIV come from?
Animation, HIV Drug Resistance
7. Reverse transcriptase mutations: NRTIs
TAMs
M184V
K65R
8. Reverse transcriptase mutations: NNRTIs
9. Protease inhibitor resistance
10. Integrase inhibitors resistance
11. Genetic barrier
12. Treatment failure
13. Second-line
A proposed schema
14. HIVResNet and Early Warning Indicators
15. Third-line
16. Resistance tests
Genotypic test
Phenotypic test
Virtual phenotype
17. References
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HIV drug resistance
Why is it important to take
ARVs
in the correct way?
© Institute of Tropical Medicine, Antwerp
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